Katarzyna Goljanek‐Whysall

This study characterizes spontaneous OA in CD1 mice, showing progression from mild to severe disease with multi-tissue pathology, establishing them as a robust model for OA research.

This study shows PRDX6 limits mitochondrial lipid peroxidation under oxidative stress, preventing MERCS formation and inflammation in both myoblasts and C. elegans.

This study shows PERK promotes MERCS formation and mitochondrial remodelling during adaptive UPR signalling in myoblasts and C. elegans, enhancing physiological function.

This study shows miR-1 regulates metabolic flexibility in skeletal muscle by controlling pyruvate metabolism, with loss of miR-1 causing metabolic inflexibility and reduced endurance.

This study identifies exercise-related microRNAs in C. elegans that regulate calcium homeostasis and mitochondrial dynamics, showing conserved pathways but divergent microRNAs across species.

This study identifies miR-379-3p as a regulator of cancer cachexia by modulating purinergic receptors, mitochondrial function, and inflammatory responses in a sex-dependent manner.

This study shows PRDX-2 regulates DAF-16/FOXO-mediated mitochondrial remodelling during exercise, which is disrupted in ageing in C. elegans.

This study identifies age- and caloric restriction-associated miRNA expression changes in rat skeletal muscle and their functional impacts on muscle cell processes.

This study uses RNA sequencing to identify gene expression changes in aged muscle and how caloric restriction affects these changes, revealing key pathways and hub genes involved in sarcopenia.

The paper shows that Peroxiredoxin 2 is essential for the beneficial adaptive response to exercise-induced oxidative stress in C. elegans.

This study identifies age-related upregulation of miR-29a and miR-34a in murine cruciate ligaments and their association with collagen expression and inflammation pathways.

The paper uses small-RNA sequencing to identify altered microRNA and snoRNA signatures in skeletal muscle of male mouse offspring from dams with low protein diets during lactation.