Glutathione S-transferases: unexpected roles in astrocyte activation and astrocyte-microglia communication during brain inflammation
Shin-ichi Kano, Eric Y. Choi, Eisuke Dohi, Indigo V. L. Rose, Daniel J. Chang, Ashley M. Wilson, Brian D. Lo, Takashi Imai, Akira Sawa
This study identifies GSTM1's role in astrocyte activation and microglia enhancement during brain inflammation, showing its impact on NF-κB and JNK pathways.
bioRxiv · Oct 7, 2017 · PreprintImmunology