The role of insulators and transcription in 3D chromatin organisation of flies
Keerthi T. Chathoth, Liudmila A Mikheeva, Gilles Crevel, Jareth C. Wolfe, Ioni Hunter, Saskia Beckett-Doyle, Sue Cotterill, Hongsheng Dai, Andrew Harrison, Nicolae Radu Zabet
This study shows that depletion of architectural proteins affects TAD organisation and gene expression in Drosophila, linking TAD reorganisation to changes in gene expression.
Genome Research · Apr 1, 2022Peer-reviewedGenomics