Author

Andrew Harrison

University of EssexORCID 0000-0002-7849-4640Unclaimed ORCID profile · follow to get notified of new preprints

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Andrew Harrison1 paper

Biology Disciplines

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Bioinformatics· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:Bayesian inference· 2 Research Focus:differential expression· 2 Assay:Hi-C· 2 Assay:bulk RNA-seq· 1 Organism:Drosophila· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

Frequent Co-Authors

Hongsheng DaiiD· 3 shared Nicolae Radu ZabetiD· 3 shared Itunu Godwin OsuntokiiD· 2 shared Yanchun BaoiD· 2 shared Gilles CreveliD· 1 shared Ioni Hunter· 1 shared Jareth C. WolfeiD· 1 shared Keerthi T. Chathoth· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersBioinformatics

Hongsheng DaiORCID

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3 papers

Recent·Most cited

HiCPotts: An R/Bioconductor package to identify significant interactions in chromosome conformation capture data and model sources of biases.

Itunu Godwin Osuntoki, Andrew Harrison, Hongsheng Dai, Yanchun Bao, Nicolae Radu Zabet

HiCPotts is an R/Bioconductor package that identifies significant chromatin interactions in Hi-C data while modeling biases using a zero-inflated Negative Binomial distribution.

Bioinformatics · Aug 31, 2026Peer-reviewedBioinformatics

ZipHiC: a novel Bayesian framework to identify enriched interactions and experimental biases in Hi-C data

Itunu Godwin Osuntoki, Andrew Harrison, Hongsheng Dai, Yanchun Bao, Nicolae Radu Zabet

ZipHiC identifies enriched interactions and experimental biases in Hi-C data using a Bayesian framework with hidden Markov random field and approximate Bayesian computation.

Bioinformatics · Jun 9, 2022Peer-reviewedBioinformatics

The role of insulators and transcription in 3D chromatin organisation of flies

Keerthi T. Chathoth, Liudmila A Mikheeva, Gilles Crevel, Jareth C. Wolfe, Ioni Hunter, Saskia Beckett-Doyle, Sue Cotterill, Hongsheng Dai, Andrew Harrison, Nicolae Radu Zabet

This study shows that depletion of architectural proteins affects TAD organisation and gene expression in Drosophila, linking TAD reorganisation to changes in gene expression.

Genome Research · Apr 1, 2022Peer-reviewedGenomics