Interphase-Arrested Drosophila Embryos Initiate Mid-Blastula Transition At A Low Nuclear-Cytoplasmic Ratio
Isaac Strong, Kai Yuan, Patrick H. O’Farrell
The paper shows that Drosophila embryos can progress through developmental stages without a rise in nuclear-cytoplasmic ratio by arresting cell cycles, revealing a regulatory cascade linking cell-cycle slowing to transcriptional activation.
bioRxiv · Jun 1, 2017 · PreprintDevelopmental Biology