Kai Yuan

NeoOmni Atlas integrates proteogenomic data to catalog tumor neoantigens across 26 cancer types, identifying novel ligands and epitopes for immunotherapy.

The paper shows that the O-GlcNAcome segregates asymmetrically during Drosophila neuroblast mitosis, influencing daughter cell fate.

This study identifies CD74+ fibroblasts as key drivers of stretch-induced keloid progression through proliferation, angiogenesis, and migration.

ERVcancer provides a database to query activation of human endogenous retroviruses across cancer types using RNA-seq data from multiple sources.

This study identifies H3K14ac as a maternal factor that recruits Eggless/SetDB1 to establish constitutive heterochromatin during early Drosophila embryogenesis.

This study shows that ancestral high-sugar diet exposure in Drosophila leads to transgenerational changes in sweet sensitivity and feeding behavior through H3K27me3 reprogramming.

The paper develops a fluorescent probe to visualize O-GlcNAcylation in Drosophila embryos, showing its decline during early development and its role in neurodevelopmental gene regulation.

The paper shows that maternal H1 can compensate for the absence of BigH1 in Drosophila embryos, supporting normal development.

The paper shows that Drosophila embryos can progress through developmental stages without a rise in nuclear-cytoplasmic ratio by arresting cell cycles, revealing a regulatory cascade linking cell-cycle slowing to transcriptional activation.