Author

Isabel Flessas

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Adrianna MaglieriiD· 1 shared Ajay NadigiD· 1 shared Autumn JohnsoniD· 1 shared Caroline BeckeriD· 1 shared Derek Hawes· 1 shared Dhara Liyanage· 1 shared Ethan Crouse· 1 shared Giulio GenoveseiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Adrianna MaglieriORCID

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1 paper

Recent·Most cited

Gene editing in "cell villages" enables exploring disease-relevant mutations in many genetic backgrounds

Rachel A. Battaglia, Sonia Bolshakova, Ilinca Mazureac, Dhara Liyanage, Noah L. Pettinari, Autumn Johnson, Ethan Crouse, Sartaj Habib, Isabel Flessas, Ajay Nadig, Derek Hawes, Matthew Tegtmeyer, Caroline Becker, Sulagna Dia Ghosh, Giulio Genovese, , Ralda Nehme

The paper uses village editing to study how genetic backgrounds affect the impact of schizophrenia-associated mutations in human neurons.

bioRxiv · Nov 8, 2025 · PreprintCell Biology