Rachel A. Battaglia

The paper uses village editing to study how genetic backgrounds affect the impact of schizophrenia-associated mutations in human neurons.

The paper shows that astrocyte-supplied cholesterol drives synaptic gene expression in neurons and induces astrocytic transcriptional responses, linking lipid metabolism to neurodevelopmental disorders.

This study identifies RNA-binding protein interactions of gigaxonin, a protein mutated in Giant Axonal Neuropathy, revealing potential mechanisms linking its dysfunction to neurodegeneration.

This study creates a Drosophila tauopathy model with the P251L mutation and uses single-cell RNA sequencing to identify molecular changes in neuronal and glial cells.

The paper identifies a conserved role for APP in proteostasis during aging through genetic and multi-omics analyses in Drosophila and human models.

The paper investigates the role of HP1 and CPC interactions in Drosophila oocyte spindle assembly and identifies their involvement in kinetochore formation and chromosome bi-orientation.