The binding sites of E2F transcription factor in Drosophila metabolic genes are functionally distinct
María Paula Zappia, Yong-Jae Kwon, Anton Westacott, Isabel Liseth, Hyun Min Lee, Abul Bashar Mir Md. Khademul Islam, Jiyeon Kim, Maxim V. Frolov
This study shows that E2F binding to the metabolic gene Pgk affects glycolytic flux, mitochondrial morphology, and lifespan in Drosophila.
bioRxiv · Nov 22, 2022 · PreprintDevelopmental Biology