Author

Isabel Rodriguez

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Genetic & Genomic Medicine· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Michael C. DeaniD· 3 shared Anton GoretskyiD· 2 shared Asher BryantiD· 2 shared Ataberk DonmeziD· 2 shared Ayşe Gökçe KeşküşiD· 2 shared Bao Quoc TraniD· 2 shared Benedict PateniD· 2 shared Brandy McNulty· 2 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenetic & Genomic Medicine

Michael C. DeanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Wakhan: reconstruction of chromosome-scale copy number profiles of tumor genomes with long-read sequencing

Tanveer Ahmad, Ayşe Gökçe Keşküş, Sergey S. Aganezov, Anton Goretsky, Isabel Rodriguez, Byunggil Yoo, Lisa A. Lansdon, Elena A. Repnikova, Lei Zhang, Yuelin Liu, Ataberk Donmez, Asher Bryant, Sonam Tulsyan, Jimin Park, Joshua Gardner, , Mikhail Kolmogorov

Wakhan reconstructs chromosome-scale copy number profiles of tumor genomes using long-read sequencing, showing better consistency with data than existing methods.

medRxiv · Dec 15, 2025 · PreprintGenetic & Genomic Medicine

Severus: accurate detection and characterization of somatic structural variation in tumor genomes using long reads

Ayşe Gökçe Keşküş, Asher Bryant, Tanveer Ahmad, Byunggil Yoo, Sergey S. Aganezov, Anton Goretsky, Ataberk Donmez, Lisa A. Lansdon, Isabel Rodriguez, Jimin Park, Yuelin Liu, Xiwen Cui, Joshua Gardner, Brandy McNulty, Samuel Sacco, , Mikhail Kolmogorov

Severus detects and characterizes somatic structural variations in tumor genomes using long reads, outperforming existing methods in accuracy and revealing clinically relevant rearrangements.

Nature Biotechnology · Apr 4, 2025Peer-reviewedGenetic & Genomic Medicine

Analysis of the progression of cervical cancer in Guatemala- from pre-malignancy to invasive disease

Emma Robinson, Isabel Rodriguez, Víctor Argueta, Yi Xie, Hong Lou, Rose Milano, Hyo‐Jung Lee, Laurie A. Burdett, Sambit Kumar Mishra, Meredith Yeager, Lisa J. Mirabello, Michael C. Dean, Roberto Orozco

This study analyzes RNA from cervical biopsies to identify gene expression changes and survival associations during cervical cancer progression in Guatemala.

Tumour Virus Research · Dec 12, 2024Peer-reviewedCancer Biology