Lisa J. Mirabello

This study identifies molecular traits distinguishing HPV+ oropharyngeal cancer recurrence, showing reduced genomic instability contributes to tumor progression and immune suppression.

This study analyzes RNA from cervical biopsies to identify gene expression changes and survival associations during cervical cancer progression in Guatemala.

The paper identifies a Neandertal introgressed haplotype in the OAS1 gene associated with increased risk of severe COVID-19 and shows it impairs SARS-CoV-2 clearance through genetic regulation of OAS1 expression.

This study shows that APOBEC mutagenesis occurs in both tumor and viral genomes in HPV+ OPSCC, suggesting a direct link between viral restriction and host mutations.