Author

Isabella Eva Randerath

RWTH Aachen University

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Neuroscience· 1

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Organism:Drosophila· 1 Approach:experimental assay· 1

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Axel MethneriD· 1 shared Bernhard MichalkeiD· 1 shared Christopher Weber· 1 shared Eva-Maria HanschmanniD· 1 shared Giuseppe ArenaiD· 1 shared Li ZhangiD· 1 shared Liliana Rojas-CharryiD· 1 shared Majd AbusaadaiD· 1 shared

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Axel MethnerORCID

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1 paper

Recent·Most cited

NeuroscienceeLifePeer-reviewedAug 19, 2024

Iron-sulfur cluster loss in mitochondrial CISD1 mediates PINK1 loss-of-function phenotypes

Sara Bitar, Timo Baumann, Christopher Weber…·Axel Methner

The paper shows that CISD1 dimerization in PINK1 mutants disrupts iron-sulfur cluster coordination, leading to Parkinson's disease-like phenotypes, and suggests CISD1 as a therapeutic target.

12 citations

Drosophilaexperimental assay

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