Bernhard Michalke

This study shows that IRP1 deficiency in mice leads to metabolic changes that protect against metabolic syndrome by altering mitochondrial function and improving insulin sensitivity.

This study evaluates the genotoxic and mutagenic effects of combustion particles from marine fuels with varying sulfur content, finding that toxicological outcomes correlate more with polycyclic aromatic hydrocarbon content than sulfur content.

The paper shows that CISD1 dimerization in PINK1 mutants disrupts iron-sulfur cluster coordination, leading to Parkinson's disease-like phenotypes, and suggests CISD1 as a therapeutic target.