Sara Bitar

This study shows that reducing ACSBG1 in astrocytes reduces inflammation and α-Synuclein pathology in a Parkinson's disease mouse model.

The paper identifies a disrupted mitochondrial-purine metabolism link in MECP2 Duplication Syndrome across multiple models, linking it to neurodevelopmental issues.

This study investigates the interaction between TMBIM5 and MICU1 in mitochondria, showing they regulate structure, calcium homeostasis, and apoptosis in Drosophila and human cells.

The paper shows that CISD1 dimerization in PINK1 mutants disrupts iron-sulfur cluster coordination, leading to Parkinson's disease-like phenotypes, and suggests CISD1 as a therapeutic target.

This study identifies how GDAP1 loss of function disrupts actin signaling, leading to mitochondrial tubularity and metabolic changes in CMT4A.