Resting calcium ion fluxes protect cells from fast mitochondrial fragmentation, cell stress responses, and immediate transcriptional reprogramming
Caroline Fecher, Annemarie Sodmann, Felicitas Schlott, Juliane Jaepel, Franziska Schmitt, Isabella Lengfelder, Thorsten Bischler, Bernhard Nieswandt, Konstanze F. Winklhofer, Robert Blum
The paper shows that resting calcium fluxes prevent mitochondrial fragmentation and transcriptional changes in astrocytes by modulating ER stress and gene expression.
Cellular and Molecular Life Sciences · Jun 14, 2025Peer-reviewedPhysiology