Poising and connectivity of emergent human developmental enhancers in the transition from naive to primed pluripotency
Marina Charlotte Nocente, Monica Della Rosa, Andrew A. Malcolm, George Lister, Isabella Savin, Helen F. Ray-Jones, Sarah Elderkin, Ruilin Tian, Simon Andrews, Adam Bendall, Claudia I. Semprich, Martin Kampmann, Valeriya Malysheva, Maria Rostovskaya, Peter J. Rugg‐Gunn, Mikhail Spivakov
The paper investigates the chromosomal contacts of poised enhancers during the transition from naive to primed human pluripotency, revealing their dynamics and functional significance.
Cell Reports · Jun 1, 2026Peer-reviewedGenomics