Unveiling Mechanistic and Structural Insights of EstS1 Esterase: A Potent Broad-Spectrum Phthalate Diester Degrading Enzyme
Shalja Verma, Shweta Choudhary, Kamble Amith Kumar, Jai Krishna Mahto, Anil Kumar Vamsi K, Ishani Mishra, Vellanki Bhanu Prakash, Debabrata Sircar, Shailly Tomar, Ashwani Kumar Sharma, Jitin Singla, Pravindra Kumar
This study characterizes the structural and mechanistic properties of EstS1 esterase, revealing its role in degrading phthalate diesters through a bi-bi ping-pong mechanism and covalent substrate binding.
Structure · Dec 5, 2024Peer-reviewedBiophysics