Ashwani Kumar Sharma

This study determines the crystal structures of a cysteine-dependent hydrolase from Rhodococcus opacus in complex with various plastics and shows its ability to degrade polyethylene, polypropylene, and polystyrene.

This paper identifies a novel bacteriophage endolysin LysPH with broad antibacterial activity and elucidates its structural basis for substrate recognition and catalytic activation.

This study identifies and characterizes the bifunctional PFP enzyme in CLas, showing its ability to catalyze both F6P to FBP and S7P to SBP reactions.

This study characterizes the structural and mechanistic properties of EstS1 esterase, revealing its role in degrading phthalate diesters through a bi-bi ping-pong mechanism and covalent substrate binding.