Transcriptional regulation by NR5A2 couples cell differentiation and inflammation in the pancreas
Isidoro Cobo, Paola Martinelli, Marta Flández, Latifa Bakiri, Mingfeng Zhang, Enrique Carrillo-de-Santa-Pau, Jinping Jia, Liv Thommesen, Torunn Bruland, Natalia del Pozo, Sara Olson, Jill Smith, William R. Bamlet, Gloria M Petersen, Núria Malats, , Francisco X Real
This study shows NR5A2 regulates both cell differentiation and inflammation in the pancreas, with its loss leading to a pre-inflammatory state and impaired regeneration.
bioRxiv · Oct 26, 2017 · PreprintCancer Biology