PhysiologyArteriosclerosis Thrombosis and Vascular BiologyPeer-reviewed
Hepatic Inactivation of Carnitine Palmitoyltransferase 1a Lowers Apolipoprotein B Containing Lipoproteins in Mice
Robert Nathaniel Helsley, Mikala M. Zelows, Victoria P. Noffsinger…·Gregory A. Graf
This study shows that reducing CPT1a in the liver lowers apoB-containing lipoproteins and cholesterol in mice, with increased clearance of these lipoproteins linked to enhanced PPAR signaling.
6 citations