Núria Malats

This study identifies NGFR as a marker of a basal BLCA subpopulation associated with poor prognosis and reduced immunotherapy response.

This paper provides methodological guidance for integrating liquid biopsy features using AI, emphasizing data preprocessing, feature selection, and model validation.

This study identifies novel genetic risk loci for pancreatic ductal adenocarcinoma in African ancestry individuals through admixture mapping and GWAS.

This paper develops a consensus molecular classifier for pancreatic ductal adenocarcinoma by integrating tumor and stroma features, achieving high accuracy in predicting overall survival.

This paper shows a CTRB2 deletion variant increases pancreatic cancer risk by causing ER stress and inflammation in mice, using a new genetic model.

The paper uses a multi-layered approach combining GWAS, spatial autocorrelation, and Hi-C to identify novel genetic variants associated with pancreatic cancer susceptibility.

This study shows NR5A2 regulates both cell differentiation and inflammation in the pancreas, with its loss leading to a pre-inflammatory state and impaired regeneration.

This paper improves polygenic risk scores by applying winners curse correction and variable thresholds to GWAS summary data, enhancing prediction accuracy for some diseases.