The non-homologous end joining factor Ku orchestrates replication fork resection and fine-tunes Rad51-mediated fork restart
Ana Teixeira-Silva, Anissia Ait Saada, Julien Hardy, Ismaïl Iraqui, Marina Charlotte Nocente, Karine Fréon, Sarah Lambert
The paper investigates how Ku coordinates fork resection and restart in Schizosaccharomyces pombe, revealing a two-step resection process and the role of Ku in fine-tuning HR-mediated replication restart.
Nature Communications · Dec 1, 2017Peer-reviewedGenetics