Canavanine-based assay for gross chromosomal rearrangements reveals genome instability hotspots and modulating genes in fission yeast
Anissia Ait Saada, Cassandre Ollivier, Alex B. Costa…·Kirill S. Lobachev
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Centre National de la Recherche ScientifiqueORCID 0000-0002-1403-3204Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
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Anissia Ait Saada, Cassandre Ollivier, Alex B. Costa…·Kirill S. Lobachev
Shrena Chakraborty, Joanna Strachan, Kamila Schirmeisen…·Sarah Lambert
Kamila Schirmeisen, Karel Naiman, Karine Fréon…·Sarah Lambert
The paper investigates how SUMO protease and proteasome recruitment at nuclear pores affects replication dynamics at arrested forks in fission yeast.
Melissa Leriche, Clara Bonnet, Jagannath Jana…·Stéphan Vagner
This study shows 53BP1 interacts with RNA primers from Okazaki fragments during DNA replication, supporting their processing and highlighting an RNA-protein interaction at replication forks.
Jakub Muraszko, Karol Kramarz, Bilge Argunhan…·Dorota Dziadkowiec
This study shows Rrp1 counteracts Rad51 activity in fission yeast through ATPase and ubiquitin ligase functions, preventing genome instability.
Julien Hardy, Dingli Day, Anissia Ait Saada…·Sarah Lambert
The paper shows that histone deposition is essential for completing recombination-dependent replication (RDR) and balancing genome stability during replication stress in fission yeast.
Ana Teixeira-Silva, Anissia Ait Saada, Julien Hardy…·Sarah Lambert
The paper investigates how Ku coordinates fork resection and restart in Schizosaccharomyces pombe, revealing a two-step resection process and the role of Ku in fine-tuning HR-mediated replication restart.