Ribosomal protein L5 (RPL5/uL18) I60V mutation is associated to increased translation and modulates drug sensitivity in T-cell acute lymphoblastic leukemia cells
Lorenza Bacci, Daniela Pollutri, Israt Jahan Ripa, Michael D’Andrea, Virginie Marchand, Yuri Motorin, Anne-Marie Hesse, Yohann Couté, Kamil Filipek, Marianna Penzo
This study investigates the RPL5-I60V mutation in T-ALL, showing it increases translation and alters drug sensitivity in leukemia cells.
Biochemical Pharmacology · Oct 31, 2025Peer-reviewedCancer Biology