Early-life infection with Cryptosporidium parvum induces inflammatory responses to dietary antigens
Iti Saraav, Wanyi Huang, Jisun Jung, Rui Xu, Yong Fu, Keely G. McDonald, Lawrence A. Schriefer, Rachel Rodgers, Megan T. Baldridge, Rodney D. Newberry, Chyi‐Song Hsieh, L. David Sibley
This study shows that early-life Cryptosporidium parvum infection in mice disrupts oral tolerance by altering regulatory T cell development and inducing TH1 immune responses to dietary antigens.
Gut Microbes · Aug 28, 2025Peer-reviewedMicrobiology