Lawrence A. Schriefer

This study identifies Trim47 as a host restriction factor that inhibits murine norovirus strain CR6 but not strain CW3, revealing strain-specific antiviral mechanisms.

This study shows that early-life Cryptosporidium parvum infection in mice disrupts oral tolerance by altering regulatory T cell development and inducing TH1 immune responses to dietary antigens.

The paper shows ATG-3 limits Orsay virus infection in C. elegans by regulating collagen pathways, independent of autophagic flux.

This study compares bacterial and viral transfer methods in mouse microbiota transplantation, finding co-housing more effective than fecal or cecal transplantation for rapid reconstitution.

This study uses barcoded viruses to show that IFN-λ and tuft cell numbers limit persistent murine norovirus infection, with distinct viral populations in intestinal and extraintestinal sites.