Phosphorothioate DNA modification by BREX Type 4 systems in the human gut microbiome
Yifeng Yuan, Michael S. DeMott, Shane R. Byrne, Katia Flores, Mathilde Poyet, Mathieu Groussin, Brittany M. Berdy, J. Rusine-Bahunde, Catherine Girard, Jenni Lehtimäki, Audax Z. P. Mabulla, Ivan Emil Mwikarago, Yvonne Ayerki Nartey, Le Thanh Tu Nguyen, Charles Asabamaka Onyekwere, , Peter C. Dedon
The paper identifies new phosphorothioate DNA modification systems in the human gut microbiome using genomic and mass spectrometric analysis.
Nature Communications · Jan 22, 2026Peer-reviewedMicrobiology