Mathieu Groussin

The paper investigates how lifestyle-associated microbiome shifts and host genetics influence gene expression in intestinal organoids, identifying microbiome-dependent allele-specific expression effects.

This study examines gut microbiome diversity and structure across different lifestyles in Thailand, finding variations in microbial composition and associations with lifestyle factors.

The paper uses genome-scale metabolic models to predict how diet and lifestyle affect microbial interactions in the gut microbiome, finding shifts from collaboration to competition with high sugar intake.

This study identifies Blautia wexlerae's role in converting dietary fats into bioactive metabolites that enhance gut hormone secretion and improve metabolic health in mice and humans.

The paper identifies new phosphorothioate DNA modification systems in the human gut microbiome using genomic and mass spectrometric analysis.

The paper compares host transcriptional responses to urban and rural gut microbiomes, finding urban microbiomes affect innate immune pathways and high-diversity microbiomes trigger stronger host responses.

This study examines how gut bacteria genomes adapt to industrialization, finding convergent genomic responses in stress response, cell envelope remodeling, and central metabolism across different populations.

This study investigates long-term intestinal epithelial changes after acute protein-energy malnutrition using multi-omics approaches and identifies microbial lipid metabolites and epigenetic factors as key drivers of persistent Paneth cell dysfunction.

The paper investigates how industrialization affects microbial and physiological traits in the human gut across diverse populations, finding homogenized microbiomes, reduced diversity, and impaired disease prediction accuracy in less industrialized groups.

This study shows gut microbiota influences disease severity in an experimental pemphigoid model, with specific taxa linked to protection or inflammation.

The paper proposes a roadmap for fair reuse of public microbiome data by introducing a Data Reuse Information tag (DRI) to facilitate communication between data creators and consumers.

The study assesses AMR gene reservoirs in human, animal, and environmental samples from a Kathmandu temporary settlement using metagenomics and network analysis.

This study shows that virus-host coexistence in phytoplankton is maintained through bet hedging, where susceptible and resistant phenotypes switch, allowing continuous growth of both microalga and virus.