Alternatively polarized neutrophils metabolically restrain macrophage-driven inflammation
Paul Ettel, Jayne Louise Wilson, Piyal Saha, Mario Mazic, Aglaja Kopf, Kveta Brazdilova, Georg Stary, Ivan Melikhov, Anne Miller, Jadwiga Jabłońska, Markus H. Hoffmann, Gernot Schabbauer, Markus Hengstschläger, Thomas Weichhart
This study identifies an arginine-dependent metabolic mechanism by which alternatively polarized neutrophils restrain macrophage-driven inflammation in mouse models and human diseases.
bioRxiv · Oct 6, 2026 · PreprintImmunology