Kveta Brazdilova

This study identifies reduced tissue-resident memory T cells and increased PD-1 expression in the KS tumor microenvironment of HIV-positive individuals, suggesting impaired antitumor immunity and potential for immune checkpoint therapy.

This study identifies an arginine-dependent metabolic mechanism by which alternatively polarized neutrophils restrain macrophage-driven inflammation in mouse models and human diseases.

This study creates a comprehensive single-cell transcriptomic atlas of human endothelial cells across adult life, identifying age-related transcriptional changes and a p21-linked senescence program.

mRNAid is an open-source software that optimizes mRNA sequences to reduce immunogenicity, improve stability, and enhance protein output.

TraceTrack is an open-source tool for batch processing, aligning, and visualizing Sanger sequencing chromatograms, offering improved functionality over existing software.