Author

J Shirly

Rajiv Gandhi Centre for Biotechnology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Arun (Geetha) ViswanathaniD· 1 shared Chenicheri Kizhakkeveettil KeerthanaiD· 1 shared Jayasekharan S. Aparna· 1 shared Kalimuthu Kalishwaralal· 1 shared Kuzhuvelil B. HarikumariD· 1 shared Lekshmi R. NathiD· 1 shared Mundanattu SwethaiD· 1 shared Nikhil Ponnoor AntoiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Arun (Geetha) ViswanathanORCID

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1 paper

Recent·Most cited

Evaluating the therapeutic efficacy of the US FDA-designated Orphan drug, uttroside B in impeding hepatocarcinogenesis via induction of immunogenic apoptosis, using a murine model of Aflatoxin B1-induced liver carcinogenesis

Mundanattu Swetha, Chenicheri Kizhakkeveettil Keerthana, Tennyson Prakash Rayginia, Kalimuthu Kalishwaralal, Sadiq Chembothumparambil Shifana, Sreekumar Usha Devi Aiswarya, Lekshmi R. Nath, Sanjay Suresh Varma, Arun (Geetha) Viswanathan, Somaraj Jannet, J Shirly, Jayasekharan S. Aparna, Sankar Sundaram, Nikhil Ponnoor Anto, Noah Isakov, , Ruby John Anto

This study evaluates uttroside B's efficacy in preventing AFB1-induced hepatocarcinogenesis in mice by inducing immunogenic apoptosis and blocking immune checkpoints.

bioRxiv · Sep 8, 2025 · PreprintCancer Biology