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Jörg G. Weiss

University of Toronto

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Genomics· 1

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Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:differential expression· 1 Approach:statistical model· 1

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Asher D. CutteriD· 1 shared Cristel G. ThomasiD· 1 shared Santiago Sanchez RamireziD· 1 shared

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GenomicsPLoS GeneticsPeer-reviewedMar 5, 2021

Widespread misregulation of inter-species hybrid transcriptomes due to sex-specific and sex-chromosome regulatory evolution

Santiago Sanchez Ramirez, Jörg G. Weiss, Cristel G. Thomas, Asher D. Cutter

The paper examines sex-specific regulatory divergence in hybrid transcriptomes of Caenorhabditis nematodes, finding widespread misexpression of sex-biased genes, especially on the X-chromosome, leading to male-specific hybrid dysfunction.

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C. elegansbulk RNA-seq

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