Asher D. Cutter

The paper analyzes the genomic diversity of C. tropicalis, finding geographic correlation and hyper-divergent regions linked to environmental adaptation.

The paper investigates gene regulatory divergence in Caenorhabditis nematode hybrids, finding that cis-regulatory divergence disproportionately affects gene expression and contributes to sex-specific hybrid dysfunction.

The paper uses in vivo parallelized reporter assays in C. elegans to identify tissue-specific splicing regulatory sequences and their functional relevance.

The paper analyzes over 2,000 Caenorhabditis briggsae wild strains to uncover genetic diversity, population structure, and evolutionary mechanisms shaping phenotypic variation.

The paper compares gene expression between two Caenorhabditis nematode species, finding that tissue-biased expression is conserved while sex-biased genes drive divergence.

The paper estimates speciation clocks in Caenorhabditis nematodes, finding post-zygotic reproductive isolation accumulates faster than pre-zygotic isolation.

The paper quantifies subcellular organelle allocation in nematode sperm using electron microscopy to determine if organelle investment correlates with sperm size evolution.

The paper surveys Argonaute genes across 51 Caenorhabditis species, identifying gene gains, losses, and functional diversification, revealing dynamic evolution of small RNA pathways.

This study identifies multiple developmental defects in hybrids of Caenorhabditis species that contribute to postzygotic reproductive isolation, but finds no evidence of premating isolation or ectopic sperm migration as barriers.

The paper examines sex-specific regulatory divergence in hybrid transcriptomes of Caenorhabditis nematodes, finding widespread misexpression of sex-biased genes, especially on the X-chromosome, leading to male-specific hybrid dysfunction.

COMPMAP is a method for allele-specific expression analysis that improves accuracy by resolving ambiguous reads using parental alignments and statistical methods.

The paper shows that genome structure influences modular transcriptome responses to genetic and environmental conditions in C. briggsae.

The paper develops a micro-droplet assay to study thermal tolerance in C. elegans, finding that genetic and developmental factors shape behavioral responses to temperature.

The paper investigates genetic factors influencing ectopic sperm migration in C. elegans, identifying ovulation dynamics and sperm guidance cues as modulators of susceptibility to sperm invasion.