GenomicsPLoS GeneticsPeer-reviewed
Widespread misregulation of inter-species hybrid transcriptomes due to sex-specific and sex-chromosome regulatory evolution
Santiago Sanchez Ramirez, Jörg G. Weiss, Cristel G. Thomas, Asher D. Cutter
The paper examines sex-specific regulatory divergence in hybrid transcriptomes of Caenorhabditis nematodes, finding widespread misexpression of sex-biased genes, especially on the X-chromosome, leading to male-specific hybrid dysfunction.
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