Thioredoxin regulates the redox state and the activity of the human tRNA ligase complex
D. Jaksch, J. Irnstorfer, P.-F. Kalman, J. A. Martinez
This study shows Thioredoxin (TRX) reduces and reactivates oxidized RTCB, a subunit of the tRNA ligase complex, under oxidative stress conditions during the UPR.
bioRxiv · May 26, 2023Biochemistry