Identifying states of collateral sensitivity during the evolution of therapeutic resistance in Ewings sarcoma
J. A. Scarborough, E. McClure, P. Anderson, A. Dhawan, A. Durmaz, S. L. Lessnick, M. Hitomi, J. G. Scott
This study maps the temporal evolution of collateral sensitivity and resistance in Ewings sarcoma, showing unpredictable patterns in drug response and highlighting transcriptomic changes associated with these states.
bioRxiv · Feb 11, 2020Evolutionary Biology