Versatile Tissue-Injectable Hydrogels with Extended Hydrolytic Release of Bioactive Protein Therapeutics
E. S. Nealy, S. J. Reed, B. A. Badeau, S. M. Adelmund, J. A. Shadish, F. J. Pakiam, E. J. Girard, J. P. Price, A. J. Mhyre, V. Kalia, S. Sarkar, C. A. DeForest, J. M. Olson
This paper develops injectable hydrogels that enable controlled, extended release of protein therapeutics through hydrolysable linkers, demonstrating efficacy in a mouse melanoma model.
bioRxiv · Sep 1, 2023 · PreprintBioengineering