Author

E. J. Girard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 1 Assay:protein sequence· 1

Frequent Co-Authors

J. M. Olson· 2 shared A. J. Mhyre· 1 shared B. A. Badeau· 1 shared C. A. DeForest· 1 shared E. S. Nealy· 1 shared F. J. Pakiam· 1 shared G. P. Sevilla· 1 shared J. A. Shadish· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBioengineering

J. M. Olson

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2 papers

Recent·Most cited

CYpHER: Catalytic extracellular targeted protein degradation with high potency and durable effect

Z. R. Crook, G. P. Sevilla, P. Young, E. J. Girard, T.-D. Phi, M. Howard, J. Price, J. M. Olson, N. W. Nairn

CYpHER is a targeted protein degradation technology that uses pH-dependent release and the transferrin receptor to deliver drugs to endolysosomes, demonstrating potency and durability in vitro and in vivo.

Nature Communications · Oct 9, 2024Peer-reviewedBioengineering

Versatile Tissue-Injectable Hydrogels with Extended Hydrolytic Release of Bioactive Protein Therapeutics

E. S. Nealy, S. J. Reed, B. A. Badeau, S. M. Adelmund, J. A. Shadish, F. J. Pakiam, E. J. Girard, J. P. Price, A. J. Mhyre, V. Kalia, S. Sarkar, C. A. DeForest, J. M. Olson

This paper develops injectable hydrogels that enable controlled, extended release of protein therapeutics through hydrolysable linkers, demonstrating efficacy in a mouse melanoma model.

bioRxiv · Sep 1, 2023 · PreprintBioengineering