Treatment of mice with IL2-complex enhances inflammasome-driven IFN-γ production and prevents lethal toxoplasmosis
A. Kupz, S. Pai, P. R. Giacomin, J. A. Whan, R. Walker, P.-M. Hammoudi, N. Smith, C. M. Miller
This study shows that IL2C treatment expands CD8+ T cells, DN T cells, and NK cells, enhancing IFN-γ production and preventing lethal toxoplasmosis in mice.
bioRxiv · Mar 29, 2019 · PreprintMicrobiology