Author

A. Kupz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. A. Robertson· 1 shared A. Chenery· 1 shared A. Loukas· 1 shared B. Govan· 1 shared B. H. Chan· 1 shared C. M. Miller· 1 shared C. Rush· 1 shared D. Brough· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperImmunology

A. A. Robertson

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Disparate effects of metformin on Mycobacterium tuberculosis infection in diabetic and non-diabetic mice

H. Sathkumara, K. Hansen, S. Miranda-Hernandez, B. Govan, C. Rush, L. Henning, N. Ketheesan, A. Kupz

This study shows that metformin has different effects on tuberculosis infection in diabetic versus non-diabetic mice, with non-diabetic mice showing higher disease burden.

Antimicrobial Agents and Chemotherapy · Dec 16, 2020Peer-reviewedMicrobiology

Inflammasome-independent role for NLRP3 in controlling innate anti-helminth immunity and tissue repair in the lung

A. Chenery, R. Alhallaf, Z. Agha, J. Ajendra, J. Parkinson, M. M. Cooper, B. H. Chan, R. M. Eichenberger, L. A. Dent, A. A. Robertson, A. Kupz, D. Brough, A. Loukas, T. E. Sutherland, J. E. Allen, P. Giacomin

This study shows NLRP3 limits lung neutrophilia and helminth killing in an inflammasome-independent way, while promoting tissue repair.

bioRxiv · Jun 7, 2019Immunology

Treatment of mice with IL2-complex enhances inflammasome-driven IFN-γ production and prevents lethal toxoplasmosis

A. Kupz, S. Pai, P. R. Giacomin, J. A. Whan, R. Walker, P.-M. Hammoudi, N. Smith, C. M. Miller

This study shows that IL2C treatment expands CD8+ T cells, DN T cells, and NK cells, enhancing IFN-γ production and preventing lethal toxoplasmosis in mice.

bioRxiv · Mar 29, 2019 · PreprintMicrobiology