Author

J. A. Wilson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Research Focus:variant calling· 1

Frequent Co-Authors

M. Panigrahi· 2 shared J. Q. Khan· 1 shared M. Palmer· 1 shared P. A. Thibault· 1 shared R. D. Kunden· 1 shared S. Ghezelbash· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 5 mutual co-author links

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2 shared papersMicrobiology

M. Panigrahi

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Author profile →

3 papers

Recent·Most cited

miR-122 affects both the initiation and maintenance of Hepatitis C Virus infections

M. Panigrahi, P. A. Thibault, J. A. Wilson

This study shows miR-122 is essential for initiating HCV infection but has a minor role in maintaining it, with implications for anti-miR-122 therapy.

bioRxiv · Nov 4, 2021Microbiology

Enhanced virus translation enables miR-122-independent Hepatitis C Virus propagation

M. Panigrahi, M. Palmer, J. A. Wilson

This study shows that HCV mutants replicating without miR-122 also replicate without other miRNAs and exhibit enhanced translation, suggesting miR-122's main role is translation stimulation and genome stabilization.

bioRxiv · Jun 8, 2021 · PreprintMicrobiology

Location specific small RNA annealing to the HCV 5' UTR promotes Hepatitis C Virus replication by favoring IRES formation and stimulating virus translation

R. D. Kunden, S. Ghezelbash, J. Q. Khan, J. A. Wilson

This study identifies how miR-122 annealing to different sites on the HCV 5' UTR affects virus replication, translation, and IRES formation, proposing that genome stabilization is not the primary mechanism.

bioRxiv · Mar 25, 2020 · PreprintMicrobiology