Author

J. Ambroise

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Microbiology· 1 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2

Frequent Co-Authors

J.-L. Gala· 2 shared L. Bertrand· 2 shared A. Geiser· 1 shared A. Ginion· 1 shared A. M. Collin· 1 shared A. Marino· 1 shared A. sentis· 1 shared B. Bearzatto· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersBioengineering

J.-L. Gala

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A NRF2/beta3-adrenoreceptor axis drives a sustained antioxidant and metabolic rewiring through the pentose-phosphate pathway to alleviate cardiac stress

L. Michel, H. Esfahani, R. Verdoy, D. de Mulder, J. Ambroise, V. Roelants, B. Bouchard, J. Savary, J. Dewulf, T. Doumont, C. Bouzin, V. Haufroid, J. J. F. P. Luiken, M. Nabben, M. Singleton, , J.-L. Balligand

This study identifies a NRF2/beta3-adrenoreceptor axis that enhances antioxidant defenses and metabolic rewiring via the pentose-phosphate pathway, protecting cardiac function under stress.

bioRxiv · Nov 10, 2023Physiology

Sodium-myo-inositol cotransporter-1, SMIT1, promotes cardiac hypertrophy and fibrosis induced by pressure overload in mice

A. Marino, J. Cumps, L. Guilbert, A. Geiser, C. Baufays, A. Ginion, L. Ferte, S. Battault, F. De Matos, J. Ambroise, C. J. Zuurbier, F. Lezoualc'h, C. Pestiaux, G. Pyka, G. Kerckhofs, , C. Beauloye

This study shows that SMIT1 promotes cardiac hypertrophy and fibrosis in mice under pressure overload by enhancing IP3/Ca2+-dependent signaling pathways.

bioRxiv · Oct 25, 2023Cell Biology

Integrating Patient Metadata and Genetic Pathogen Data: Advancing Pandemic Preparedness with a Multi-Parametric Simulator

M. Bonjean, J. Ambroise, M. Connolly, J. Hayes, J. Hurel, A. sentis, F. Orchard, J.-L. Gala

This paper develops a multi-parametric simulator to link genetic pathogen data with patient metadata, enhancing pandemic preparedness through synthetic data generation and scenario customization.

bioRxiv · Aug 22, 2023 · PreprintBioengineering

The di-symbiotic systems in the aphids Sipha maydis and Peryphillus lyropictus provide a contrasting picture of recent co-obligate nutritional endosymbiosis in aphids

F. Renoz, J. Ambroise, B. Bearzatto, S. Fakhour, N. Parisot, M. Ribeiro Lopes, J.-L. Gala, F. Calevro, T. Hance

This study compares the metabolic and anatomical integration of two recently acquired nutritional symbionts in two aphid species, revealing distinct coevolutionary processes.

bioRxiv · Jun 12, 2022 · PreprintMicrobiology

The memory of airway epithelium damage in smokers and COPD patients

F. M. Carlier, B. Detry, M. Lecocq, A. M. Collin, T. Plante-Bordeneuve, S. E. Verleden, M. Delos, B. Rondelet, W. Janssens, J. Ambroise, B. M. Vanaudenaerde, S. T. Gohy, C. Pilette

This study shows that airway epithelium from smokers and COPD patients retains memory of damage, with persistent structural and functional abnormalities in vitro.

bioRxiv · Apr 21, 2021Pathology