Author

J.-L. Balligand

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Physiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

H. Esfahani· 3 shared C. Bouzin· 2 shared C. Dessy· 2 shared L. Bertrand· 2 shared A. Haase· 1 shared A. K. Bergmann· 1 shared B. Bouchard· 1 shared B. Stapel· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersPhysiology

H. Esfahani

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A matter of food and substrain: obesogenic diets induce differential severity of cardiac remodeling and diastolic dysfunction in C57Bl/6J and C57Bl/6N substrains

L. Cascarano, H. Esfahani, P. Michel, C. Bouzin, C. Dessy, J.-L. Balligand, L. Y. M. Michel

This study compares cardiac remodeling and diastolic dysfunction in C57Bl/6J and C57Bl/6N mice on obesogenic diets, finding strain-specific responses to diet.

bioRxiv · Mar 15, 2024 · PreprintPhysiology

A NRF2/beta3-adrenoreceptor axis drives a sustained antioxidant and metabolic rewiring through the pentose-phosphate pathway to alleviate cardiac stress

L. Michel, H. Esfahani, R. Verdoy, D. de Mulder, J. Ambroise, V. Roelants, B. Bouchard, J. Savary, J. Dewulf, T. Doumont, C. Bouzin, V. Haufroid, J. J. F. P. Luiken, M. Nabben, M. Singleton, , J.-L. Balligand

This study identifies a NRF2/beta3-adrenoreceptor axis that enhances antioxidant defenses and metabolic rewiring via the pentose-phosphate pathway, protecting cardiac function under stress.

bioRxiv · Nov 10, 2023Physiology

Increased prostaglandin-D2 in male but not female STAT3-deficient hearts shifts cardiac progenitor cells from endothelial to white adipocyte differentiation

E. Stelling, M. Ricke-Hoch, S. Erschow, S. Hoffman, A. K. Bergmann, M. Heimerl, S. Pietzsch, K. Battmer, A. Haase, B. Stapel, M. Scherr, O. Binah, J.-L. Balligand, D. Hilfiker-Kleiner

This study shows that male STAT3-deficient hearts have increased PGD2 secretion, leading to epigenetic changes in cardiac progenitor cells that shift their differentiation from endothelial to white adipocyte.

PLOS Biology · Dec 28, 2020Peer-reviewedCell Biology

Beta-3 Adrenoreceptors protect from hypertrophic remodelling through AMP-Activated Protein Kinase and Autophagy.

E. Dubois-Deruy, R. Gelinas, C. Beauloye, H. Esfahani, C. Dessy, L. Bertrand, J.-L. Balligand

This study shows that beta3-adrenergic receptors reduce cardiac hypertrophy by activating AMPK and preserving autophagy in both in vitro and in vivo models.

bioRxiv · Jan 14, 2020Cell Biology