The coronavirus proofreading exoribonuclease mediates extensive viral recombination
J. Gribble, A. J. Pruijssers, M. L. Agostini, J. Anderson-Daniels, J. D. Chappell, X. Lu, L. J. Stevens, A. L. Routh, M. R. Denison
This study shows that the coronavirus proofreading exoribonuclease nsp14-ExoN is essential for RNA recombination and generates defective viral genomes.
bioRxiv · Apr 23, 2020Microbiology