Author

J. B. DeGrandchamp

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Biophysics· 1

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Approach:experimental assay· 1

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A. A. Lee· 1 shared H. Ren· 1 shared J. T. Groves· 1 shared L. N. Lew· 1 shared N. H. Kim· 1 shared S. Alvarez· 1 shared

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2023-2023 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiophysics

A. A. Lee

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1 paper

Recent·Most cited

Bimodality in Ras signaling originates from processivity of the Ras activator SOS without classic kinetic bistability

A. A. Lee, N. H. Kim, S. Alvarez, H. Ren, J. B. DeGrandchamp, L. N. Lew, J. T. Groves

The paper shows that Ras signaling bimodality arises from SOS processivity, not kinetic bistability, and is controlled by scaffold protein condensation.

bioRxiv · Jul 17, 2023 · PreprintBiophysics