Author

J. Breed

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

C. Phillips· 1 shared D. Cascio· 1 shared E. S. Gleave· 1 shared J. E. Debreczeni· 1 shared K. Meador· 1 shared M. A. Arbing· 1 shared M. Gee· 1 shared M. R. Sawaya· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

C. Phillips

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1 paper

Recent·Most cited

Rigidified Scaffolds for 3-Angstrom Resolution Cryo-EM of Small Therapeutic Protein Targets

R. Castells-Graells, K. Meador, M. A. Arbing, M. R. Sawaya, M. Gee, D. Cascio, E. S. Gleave, J. E. Debreczeni, J. Breed, C. Phillips, T. O. Yeates

This paper demonstrates that rigidified scaffolds enable 3-angstrom resolution cryo-EM for small therapeutic proteins like KRAS, overcoming size limitations in structural characterization.

bioRxiv · Sep 18, 2022Biochemistry