J. Broughton

Suppression of bacterial cell death underlies the antagonistic interaction between ciprofloxacin and tetracycline in Escherichia coli

The paper quantifies the antagonistic interaction between ciprofloxacin and tetracycline at the single-cell level in Escherichia coli, showing that improved growth under the combination is due to increased survival of cells with low SOS response.

Growth-dependent heterogeneity in the DNA damage response in Escherichia coli

This study shows that in E. coli, slow growth leads to more cells with high SOS response activation despite faster SOS induction in fast growth.