M. El Karoui

Estimating mutation rates under heterogeneous stress responses

This paper develops a population dynamic model to estimate mutation rate increases under heterogeneous stress responses in bacteria, showing it can accurately infer mutation rate changes when stress responses also reduce division rates.

Growth-dependent heterogeneity in the DNA damage response in Escherichia coli

This study shows that in E. coli, slow growth leads to more cells with high SOS response activation despite faster SOS induction in fast growth.