T. Pilizota

Environmental conditions define theenergetics of bacterial dormancy and itsantibiotic susceptibility

The paper investigates how environmental conditions affect the energy states of dormant bacterial cells and their susceptibility to antibiotics.

The proton motive force determines Escherichia coli's robustness to extracellular pH

This study shows that the proton motive force (PMF) in E. coli determines its ability to maintain cytoplasmic pH under varying extracellular pH conditions.

Coordination of gene expression with cell size enables Escherichia coli to efficiently maintain motility across conditions

This study shows E. coli upregulates motility genes at slow growth to maintain flagella number and motility, while larger cell size at fast growth optimizes resource allocation.

Growth-dependent heterogeneity in the DNA damage response in Escherichia coli

This study shows that in E. coli, slow growth leads to more cells with high SOS response activation despite faster SOS induction in fast growth.

Dynamic clustering regulates activity of mechanosensitive membrane channels

The paper develops a model showing that mechanosensitive channels cluster under stress, leading to inactivation and protecting the cell from cytoplasmic loss.

Escherichia coli’s physiology can turn membrane voltage dyes into actuators

The paper develops a workflow to characterize Nernstian membrane voltage dyes in E. coli, identifying conditions where dyes act as actuators rather than probes.