N-glycosylation profiles of the SARS-CoV-2 spike D614G mutant and its ancestral protein characterized by advanced mass spectrometry
D. Wang, B. Zhou, T. Keppel, M. Solano, J. Baudys, J. Goldstein, M. G. Finn, X. Fan, A. P. Chapman, J. Bundy, A. R. Woolfitt, S. Osman, J. L. Pirkle, D. E. Wentworth, J. R. Barr
This study compares N-glycosylation profiles of SARS-CoV-2 spike proteins with D614G mutation and ancestral form using mass spectrometry, finding changes in glycan distribution and complexity.
bioRxiv · Jul 26, 2021Biochemistry